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1.
Policy Futures in Education ; 2022.
Article in English | Web of Science | ID: covidwho-2098253

ABSTRACT

The 2020 global pandemic ushered in an unparalleled call to dramatically shift the focus of how school administrators responded to the COVID-19 pandemic. The transition needed to ensure the continuity of instruction in a distance learning environment demanded a new level of urgency. The long-term impact of COVID-19 presents new leadership challenges and continues to amplify the need for change during the global health crisis. This study aimed to understand the preparedness of school administrators in the United States of America as they responded to the worldwide pandemic and their perceived opportunities and challenges during the COVID-19 pandemic. This case study collected data from a survey and interviews to investigate how school leaders rose to the occasion while working through unprecedented challenges. The findings revealed several new opportunities: visionary leadership, resources to address disparities, increased community partnerships, and innovative instructional models. The challenges faced by school leaders encompassed the digital divide, staffing shortages, online instructional practices, communication with families, and staff professional development. This study offers specific implications for school leaders and educational leadership preparation programs.

2.
Online Soc Netw Media ; 22: 100125, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1104207

ABSTRACT

The recent SARS-CoV-2 pandemic gave rise to management approaches using mobile apps for contact tracing. The corresponding apps track individuals and their interactions, to facilitate alerting users of potential infections well before they become infectious themselves. Naïve implementation obviously jeopardizes the privacy of health conditions, location, activities, and social interaction of its users. A number of protocol designs for colocation tracking have already been developed, most of which claim to function in a privacy preserving manner. However, despite claims such as "GDPR compliance", "anonymity", "pseudonymity" or other forms of "privacy", the authors of these designs usually neglect to precisely define what they (aim to) protect. We make a first step towards formally defining the privacy notions of proximity tracing services, especially with regards to the health, (co-)location, and social interaction of their users. We also give a high-level intuition of which protection the most prominent proposals likely can and cannot achieve. This initial overview indicates that all proposals include some centralized services, and none protects identity and (co-)locations of infected users perfectly from both other users and the service provider.

4.
Science ; 370(6513): 203-208, 2020 10 09.
Article in English | MEDLINE | ID: covidwho-725709

ABSTRACT

The spike protein (S) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is required for cell entry and is the primary focus for vaccine development. In this study, we combined cryo-electron tomography, subtomogram averaging, and molecular dynamics simulations to structurally analyze S in situ. Compared with the recombinant S, the viral S was more heavily glycosylated and occurred mostly in the closed prefusion conformation. We show that the stalk domain of S contains three hinges, giving the head unexpected orientational freedom. We propose that the hinges allow S to scan the host cell surface, shielded from antibodies by an extensive glycan coat. The structure of native S contributes to our understanding of SARS-CoV-2 infection and potentially to the development of safe vaccines.


Subject(s)
Betacoronavirus/chemistry , Molecular Dynamics Simulation , Spike Glycoprotein, Coronavirus/chemistry , Cryoelectron Microscopy , Electron Microscope Tomography , Glycosylation , Humans , Protein Domains , Protein Multimerization , SARS-CoV-2
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